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Case #2
Demographics: 2 years old, Male
Indication: Pain with walking

Case #2

Findings

Diagnosis

Leukemic bone involvement

Sample Report

Subtle lucent metaphyseal band in the proximal left femur, which is nonspecific and can be seen in the setting of systemic illness, congenital infections, or malignancy (particularly leukemia and neuroblastoma).

No acute fracture or malalignment.

Discussion

  • Bone changes of leukemia can be very subtle, and in this case the child already had a diagnosis of leukemia. However, the diagnosis of leukemia is sometimes first considered based on radiographic findings, so be on the lookout
  • Leukemic bone involvement can result in many different appearances including:
    • Lucent metaphyseal bands (most common)
    • Periosteal reaction
    • Osteopenia
    • Lytic lesions with wide zone of transition
    • Sclerotic lesions (thought to relate to secondary bone infarcts)
    • Vertebral compression fractures

Annotated Images & Illustrations

Red arrows: subtle lucent metaphyseal band.

Red arrows: subtle lucent metaphyseal band.

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