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Case #1

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Demographics: 38 years old, Male
Indication: Seizure

Case #1

Findings

  • T1 hypointense, T2 hyperintense expansile mass extending to the cortex in the left superior frontal gyrus
  • Mixed hyperintense and isointense internal FLAIR signal
  • No corresponding enhancement, restricted diffusion, or susceptibility artifact
  • Mild corresponding local mass effect without midline shift or evidence of herniation or hydrocephalus

Annotated Images & Illustrations

The T2-FLAIR mismatch sign: the lesion demonstrates internal T2 signal hyperintensity (red arrow) contrasted to relatively hypointense FLAIR signal (yellow arrow).

The T2-FLAIR mismatch sign: the lesion demonstrates internal T2 signal hyperintensity (red arrow) contrasted to relatively hypointense FLAIR signal (yellow arrow).

Diagnosis

IDH-mutant astrocytoma

Differential Diagnosis

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Pearls

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