影像所见
CT
- Ill-defined hyperattenuating mass in the superior aspect of the right cerebellar hemisphere
- Surrounding parenchymal edema
- Corresponding mass effect with crowding of the fourth ventricle and displacement of the cerebellar tonsils 13 mm below the foramen magnum
- Likely mild corresponding obstructive hydrocephalus
MRI
- Ill-defined T2/FLAIR hyperintense mass in the superior aspect of the right cerebellar hemisphere and superior aspect of the vermis measuring approximately 4.3 x 2.2 x 4.2 cm
- Nodular internal areas of restricted diffusion and corresponding patchy enhancement
- Peripheral susceptibility artifact about one of these nodular areas in the anterior aspect of the right cerebellar hemisphere, likely relating to hemorrhage
- Thickening and enhancement of the adjacent tentorial leaflet
- FLAIR signal hyperintensity in a right occipital sulcus and possible adjacent cortical FLAIR signal hyperintensity without definite corresponding restricted diffusion or enhancement (possibly representing leptomeningeal spread)
- Small focus of restricted diffusion along the falx without definite corresponding enhancement (also possibly a leptomeningeal tumor deposit)
- Associated mass effect in the posterior fossa resulting in cerebellar tonsillar herniation and crowding of the fourth ventricle with mild obstructive hydrocephalus
诊断
Medulloblastoma - most likely SHH-activated (TP53 wild-type) or Group 4
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