๋ฉ”์ธ ์ฝ˜ํ…์ธ ๋กœ ๊ฑด๋„ˆ๋›ฐ๊ธฐ
Case #11

PRO ํ”Œ๋žœ ํ•„์š”

PRO ๋ฉค๋ฒ„์‹ญ์œผ๋กœ ์ด ์ผ€์ด์Šค ์ž ๊ธˆ ํ•ด์ œ

ํ™˜์ž ์ •๋ณด: 22 ์„ธ, ๋‚จ์„ฑ
์ ์‘์ฆ: Headache

์†Œ๊ฒฌ

CT

  • Ill-defined hyperattenuating mass in the superior aspect of the right cerebellar hemisphere
  • Surrounding parenchymal edema
  • Corresponding mass effect with crowding of the fourth ventricle and displacement of the cerebellar tonsils 13 mm below the foramen magnum
  • Likely mild corresponding obstructive hydrocephalus

MRI

  • Ill-defined T2/FLAIR hyperintense mass in the superior aspect of the right cerebellar hemisphere and superior aspect of the vermis measuring approximately 4.3 x 2.2 x 4.2 cm
  • Nodular internal areas of restricted diffusion and corresponding patchy enhancement
  • Peripheral susceptibility artifact about one of these nodular areas in the anterior aspect of the right cerebellar hemisphere, likely relating to hemorrhage
  • Thickening and enhancement of the adjacent tentorial leaflet
  • FLAIR signal hyperintensity in a right occipital sulcus and possible adjacent cortical FLAIR signal hyperintensity without definite corresponding restricted diffusion or enhancement (possibly representing leptomeningeal spread)
  • Small focus of restricted diffusion along the falx without definite corresponding enhancement (also possibly a leptomeningeal tumor deposit)
  • Associated mass effect in the posterior fossa resulting in cerebellar tonsillar herniation and crowding of the fourth ventricle with mild obstructive hydrocephalus

์ง„๋‹จ

Medulloblastoma - most likely SHH-activated (TP53 wild-type) or Group 4

๊ฐ๋ณ„์ง„๋‹จ

๊ฐ๋ณ„ ์ง„๋‹จ์„ ์ž ๊ธˆ ํ•ด์ œํ•˜๋ ค๋ฉด PRO ๋ฉค๋ฒ„๊ฐ€ ๋˜์„ธ์š”

ํ•ต์‹ฌ ํฌ์ธํŠธ

ํ•ต์‹ฌ ํŒ์„ ์ž ๊ธˆ ํ•ด์ œํ•˜๋ ค๋ฉด PRO ๋ฉค๋ฒ„๊ฐ€ ๋˜์„ธ์š”

์ฐธ๊ณ ๋ฌธํ—Œ

์‚ฌ์ดํŠธ ํ”ผ๋“œ๋ฐฑ

์—ฌ๋Ÿฌ๋ถ„์˜ ํ”ผ๋“œ๋ฐฑ์€ CaseStacks ๊ฐœ์„ ์— ๋„์›€์ด ๋ฉ๋‹ˆ๋‹ค. ์˜๊ฒฌ, ์ œ์•ˆ ๋˜๋Š” ๋ฐœ์ƒํ•œ ๋ฌธ์ œ๋ฅผ ๊ณต์œ ํ•ด ์ฃผ์„ธ์š”.

/5
ํ”ผ๋“œ๋ฐฑ์„ ๋ณด๋‚ด์ฃผ์…”์„œ ๊ฐ์‚ฌํ•ฉ๋‹ˆ๋‹ค. ์†Œ์ค‘ํžˆ ๋ฐ˜์˜ํ•˜๊ฒ ์Šต๋‹ˆ๋‹ค.