๋ฉ”์ธ ์ฝ˜ํ…์ธ ๋กœ ๊ฑด๋„ˆ๋›ฐ๊ธฐ
์ฆ๋ก€ #1
1/30
ํ™˜์ž ์ •๋ณด: 38 ์„ธ, ๋‚จ์„ฑ
์ ์‘์ฆ: ๋ฐœ์ž‘

์ฆ๋ก€ #1

๋ฌด๋ฃŒ
๋ชจ๋‘ ๋ณด๊ธฐ

์†Œ๊ฒฌ

  • ์ขŒ์ธก ์ƒ์ „๋‘ํšŒ์˜ ํ”ผ์งˆ๊นŒ์ง€ ํ™•์žฅ๋˜๋Š” T1 ์ €์‹ ํ˜ธ, T2 ๊ณ ์‹ ํ˜ธ ํŒฝ์ฐฝ์„ฑ ์ข…๊ดด
  • ํ˜ผํ•ฉ ๊ณ ์‹ ํ˜ธ ๋ฐ ๋“ฑ์‹ ํ˜ธ์˜ ๋‚ด๋ถ€ FLAIR ์‹ ํ˜ธ
  • ๋Œ€์‘ํ•˜๋Š” ์กฐ์˜์ฆ๊ฐ•, ํ™•์‚ฐ ์ œํ•œ ๋˜๋Š” ์žํ™”์œจ ์ธ๊ณต๋ฌผ ์—†์Œ
  • ์ •์ค‘์„  ํŽธ์œ„ ๋˜๋Š” ํƒˆ์ถœ์ด๋‚˜ ์ˆ˜๋‘์ฆ์˜ ์ฆ๊ฑฐ ์—†์ด ๊ฒฝ๋„ ๊ตญ์†Œ ์ข…๊ดด ํšจ๊ณผ

์ฃผ์„์ด ์žˆ๋Š” ์ด๋ฏธ์ง€ ๋ฐ ์ผ๋Ÿฌ์ŠคํŠธ

The T2-FLAIR mismatch sign: the lesion demonstrates internal T2 signal hyperintensity (red arrow) contrasted to relatively hypointense FLAIR signal (yellow arrow).

The T2-FLAIR mismatch sign: the lesion demonstrates internal T2 signal hyperintensity (red arrow) contrasted to relatively hypointense FLAIR signal (yellow arrow).

์ง„๋‹จ

IDH ๋ณ€์ดํ˜• ์„ฑ์ƒ์„ธํฌ์ข…

๊ฐ๋ณ„์ง„๋‹จ

  • ๋ฐฐ์•„ํ˜•์„ฑ ์‹ ๊ฒฝ์ƒํ”ผ์ข…์–‘(DNET) - ์ด ์ฆ๋ก€๋Š” ์‹ค์ œ๋กœ DNET์˜ ๋งค์šฐ ์ข‹์€ ์–‘์ƒ์„ ๋ณด์ด๋ฉฐ, ๊ตฌ์ฒด์ ์œผ๋กœ ๊ฑฐํ’ˆ์ƒ ๋‚ด๋ถ€ T2 ์‹ ํ˜ธ ๊ณ ๊ฐ•๋„, FLAIR์—์„œ์˜ ์‹ ํ˜ธ ์–ต์ œ, ์กฐ์˜์ฆ๊ฐ•์˜ ๊ฒฐ์—ฌ๊ฐ€ ํ•ด๋‹นํ•จ. DNET๋Š” ์ด ์ฆ๋ก€์˜ ์ข…์–‘๋ณด๋‹ค ํ”ํžˆ ๋” ์ž‘์Œ
  • ์‹ ๊ฒฝ์ ˆ๊ต์ข… - ์ด ์ข…์–‘๋„ ์ข…์ข… ํ‘œ์žฌ์„ฑ์ด์ง€๋งŒ, ํ”ํžˆ ์กฐ์˜์ฆ๊ฐ•์„ ๋ณด์ด๊ณ  ์„ํšŒํ™”๋ฅผ ๋™๋ฐ˜ํ•จ. ์ด ์ข…์–‘์€ ์ธก๋‘์—ฝ์„ ๋” ๋นˆ๋ฒˆํžˆ ์นจ๋ฒ”ํ•จ
  • ํ•์ง€๊ต์ข… - ์ด ์ข…์–‘๋„ ํ‘œ์žฌ์„ฑ์ผ ์ˆ˜ ์žˆ์œผ๋ฉฐ, ํ”ํžˆ ์„ํšŒํ™”ํ•˜๊ณ  ๋•Œ๋•Œ๋กœ ์กฐ์˜์ฆ๊ฐ•์„ ๋ณด์ž„. T2-FLAIR ๋ถˆ์ผ์น˜ ์ง•ํ›„(T2 ๊ณ ์‹ ํ˜ธ์— ๋Œ€๋น„๋˜๋Š” FLAIR ๋“ฑ์‹ ํ˜ธ ๋˜๋Š” ์ €์‹ ํ˜ธ)๋Š” 1p19q ์˜จ์ „ํ•œ ์„ฑ์ƒ์„ธํฌ์ข…์— ์ „ํ˜•์ ์ด์ง€๋งŒ, ํ•์ง€๊ต์ข…์—๋Š” ์ „ํ˜•์ ์ด์ง€ ์•Š์Œ

ํ•ต์‹ฌ ํฌ์ธํŠธ

  • ๋ชจ๋“  ํ‘œ์žฌ์„ฑ ์ข…์–‘์€ ๋ฐœ์ž‘์œผ๋กœ ๋ฐœํ˜„ํ•  ์ˆ˜ ์žˆ์Œ
  • T2-FLAIR ๋ถˆ์ผ์น˜ ์ง•ํ›„๋Š” ์„ฑ์ƒ์„ธํฌ์ข…๊ณผ DNET ๋ชจ๋‘์—์„œ ๊ด€์ฐฐ๋  ์ˆ˜ ์žˆ์œผ๋‚˜, ํ•์ง€๊ต์ข…์—๋Š” ์ „ํ˜•์ ์ด์ง€ ์•Š์Œ

์ฐธ๊ณ ๋ฌธํ—Œ

  • Juratli T, Tummala S, Riedl A, et al. Radiographic assessment of contrast enhancement and T2/FLAIR mismatch sign in lower grade gliomas: correlation with molecular groups. J Neurooncol 2018; 141(2): 327-335.
  • Larsen J, Wharton SB, McKevitt F, Romanowski C, Bridgewater, C, Zaki H, Hoggard N. โ€˜Low grade gliomaโ€™: an update for radiologists. Br J Radiol 2017; 90: 20160600.

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