๋ฉ”์ธ ์ฝ˜ํ…์ธ ๋กœ ๊ฑด๋„ˆ๋›ฐ๊ธฐ
์ฆ๋ก€ #30

PRO ํ”Œ๋žœ ํ•„์š”

PRO ๋ฉค๋ฒ„์‹ญ์œผ๋กœ ์ด ์ผ€์ด์Šค ์ž ๊ธˆ ํ•ด์ œ

ํ”Œ๋žœ ๋ณด๊ธฐ ๋กœ๊ทธ์ธ
์ธ๊ตฌ ํ†ต๊ณ„ํ•™: Female
์ง€์‹œ์‚ฌํ•ญ: ๋‹ค๋ฐœ์„ฑ ๊ฒฝํ™”์ฆ, PML ์ตœ๊ทผ ์ง„๋‹จ

์ฆ๋ก€ #30

๊ฒฐ๊ณผ

  • ์ขŒ์ธก ์ „๋‘์—ฝ ๋ฐ ๋‘์ •์—ฝ ์ „๋ฐ˜์— ๊ฑธ์ณ ์ขŒ์ธก ๋‚ด๋‚ญ ํ›„๊ฐ ๋ฐ ๋ณต์™ธ์ธก ์ขŒ์ธก ์‹œ์ƒ๊นŒ์ง€ ์—ฐ์žฅ๋˜๋Š” T2/FLAIR ์‹ ํ˜ธ ๊ณผ๊ฐ•๋„์˜ ํ˜„์ €ํ•œ ์ฆ๊ฐ€
  • ๊ด€๋ จ ์กฐ์˜์ฆ๊ฐ• ๋˜๋Š” ํ™•์‚ฐ ์ œํ•œ ์—†์Œ(์ธ๊ณต๋ฌผ๋กœ ์ธํ•ด ํ™•์‚ฐ ์˜์ƒ์ด ์ €ํ•˜๋˜์—ˆ์ง€๋งŒ)
  • ์ •์ค‘์„  ํŽธ์œ„, ํƒˆ์ถœ ๋˜๋Š” ์ˆ˜๋‘์ฆ ์—†์ด ๊ฒฝ๋„์˜ ๊ด€๋ จ ์ข…๊ดด ํšจ๊ณผ
  • ์–‘์ธก ๋Œ€๋‡Œ ๋ฐ˜๊ตฌ, ๋‡Œ๊ต ๋ฐ ์ค‘์†Œ๋‡Œ๊ฐ์„ ์นจ๋ฒ”ํ•˜๋Š” ์ถ”๊ฐ€ T2/FLAIR ๊ณ ์‹ ํ˜ธ ๋ณ‘๋ณ€์€ ์™ธ๊ด€์ด ์œ ์‚ฌ
  • ๊ธ‰์„ฑ ๊ฒฝ์ƒ‰ ๋˜๋Š” ์ถœํ˜ˆ์˜ ์†Œ๊ฒฌ ์—†์Œ

์ง„๋‹จ

๋ฉด์—ญ ์žฌ๊ตฌ์„ฑ ์—ผ์ฆ ์ฆํ›„๊ตฐ(IRIS)

์ƒ˜ํ”Œ ๋ณด๊ณ ์„œ

์ขŒ์ธก ์ „๋‘์—ฝ ๋ฐ ๋‘์ •์—ฝ ์ „๋ฐ˜์— ๊ฑธ์ณ ์ขŒ์ธก ๋‚ด๋‚ญ ํ›„๊ฐ ๋ฐ ๋ณต์™ธ์ธก ์ขŒ์ธก ์‹œ์ƒ๊นŒ์ง€ ์—ฐ์žฅ๋˜๋Š” ์กฐ์˜์ฆ๊ฐ• ์—†์ด T2/FLAIR ์‹ ํ˜ธ ๊ณผ๊ฐ•๋„์˜ ํ˜„์ €ํ•œ ์ฆ๊ฐ€๋กœ, ๋ณ€ํ™”์˜ ๊ธ‰๊ฒฉํ•จ์„ ๊ณ ๋ คํ•  ๋•Œ ๋‹ค๋ฐœ์„ฑ ๊ฒฝํ™”์ฆ ์น˜๋ฃŒ ์ค‘์ธ ์ด ํ™˜์ž์—์„œ ๋ฉด์—ญ ์žฌ๊ตฌ์„ฑ ์—ผ์ฆ ์ฆํ›„๊ตฐ(IRIS)์„ ๊ฐ€์žฅ ๊ฐ€๋Šฅ์„ฑ์ด ๋†’๊ฒŒ ๋‚˜ํƒ€๋ƒ…๋‹ˆ๋‹ค.

์–‘์ธก ๋Œ€๋‡Œ ๋ฐ˜๊ตฌ, ๋‡Œ๊ต ๋ฐ ์ค‘์†Œ๋‡Œ๊ฐ์„ ์นจ๋ฒ”ํ•˜๋Š” ์ถ”๊ฐ€ T2/FLAIR ๊ณ ์‹ ํ˜ธ ๋ณ‘๋ณ€์€ ์™ธ๊ด€์ด ์œ ์‚ฌํ•˜๋ฉฐ, ๋งŒ์„ฑ ํƒˆ์ˆ˜์ดˆ ๋ณ‘๋ณ€์— ํ•ฉ๋‹นํ•ฉ๋‹ˆ๋‹ค.

์ •์ค‘์„  ํŽธ์œ„, ํƒˆ์ถœ ๋˜๋Š” ์ˆ˜๋‘์ฆ ์—†์ด ๊ฒฝ๋„์˜ ๊ด€๋ จ ์ข…๊ดด ํšจ๊ณผ.

๊ธ‰์„ฑ ๊ฒฝ์ƒ‰ ๋˜๋Š” ์ถœํ˜ˆ์˜ ์†Œ๊ฒฌ ์—†์Œ.

ํ† ๋ก 

PRO ํ”Œ๋žœ ํ•„์š”

PRO ๋ฉค๋ฒ„์‹ญ์œผ๋กœ ํ† ๋ก  ์ž ๊ธˆ ํ•ด์ œ

ํ”Œ๋žœ ๋ณด๊ธฐ

์ฐธ๊ณ ๋ฌธํ—Œ

  • Metz I, Radue EW, Oterino A, Kรผmpfel T, Wiendl H, Schippling S, Kuhle J, Sahraian MA, Gray F, Jakl V, Hรคusler D, Brรผck W. Pathology of immune reconstitution inflammatory syndrome in multiple sclerosis with natalizumab-associated progressive multifocal leukoencephalopathy.ย Acta Neuropatholย 2012 Feb;123(2): 235-245.
  • Post MJD, Thurnher MM, Clifford DB, Nath A, Gonzalez RG, Gupta RK, Post KK. CNS-immune reconstitution inflammatory syndrome in the setting of HIV infection, part 1: overview and discussion of progressive multifocal leukoencephalopathy-immune reconstitution inflammatory syndrome and cryptococcal-immune reconstitution inflammatory syndrome. AJNR Am J Neuroradiol 2013; 34(7): 1297-1307.
  • Post MJ, Thurnher MM, Clifford DB, Nath A, Gonzalez RG, Gupta RK, Post KK.ย CNS-immune reconstitution inflammatory syndrome in the setting of HIV infection, part 2: discussion of neuro-immune reconstitution inflammatory syndrome with and without other pathogens. AJNR Am J Neuroradiol 2013; 34(7): 1308-1318.

    • ์‚ฌ์ดํŠธ ํ”ผ๋“œ๋ฐฑ

    ์—ฌ๋Ÿฌ๋ถ„์˜ ํ”ผ๋“œ๋ฐฑ์€ CaseStacks ๊ฐœ์„ ์— ๋„์›€์ด ๋ฉ๋‹ˆ๋‹ค. ์˜๊ฒฌ, ์ œ์•ˆ ๋˜๋Š” ๋ฐœ์ƒํ•œ ๋ฌธ์ œ๋ฅผ ๊ณต์œ ํ•ด ์ฃผ์„ธ์š”.

    /5
    ํ”ผ๋“œ๋ฐฑ์„ ๋ณด๋‚ด์ฃผ์…”์„œ ๊ฐ์‚ฌํ•ฉ๋‹ˆ๋‹ค. ์†Œ์ค‘ํžˆ ๋ฐ˜์˜ํ•˜๊ฒ ์Šต๋‹ˆ๋‹ค.