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Case #11

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Dati demografici: 22 anni, Maschio
Indicazione: Headache

Reperti

CT

  • Ill-defined hyperattenuating mass in the superior aspect of the right cerebellar hemisphere
  • Surrounding parenchymal edema
  • Corresponding mass effect with crowding of the fourth ventricle and displacement of the cerebellar tonsils 13 mm below the foramen magnum
  • Likely mild corresponding obstructive hydrocephalus

MRI

  • Ill-defined T2/FLAIR hyperintense mass in the superior aspect of the right cerebellar hemisphere and superior aspect of the vermis measuring approximately 4.3 x 2.2 x 4.2 cm
  • Nodular internal areas of restricted diffusion and corresponding patchy enhancement
  • Peripheral susceptibility artifact about one of these nodular areas in the anterior aspect of the right cerebellar hemisphere, likely relating to hemorrhage
  • Thickening and enhancement of the adjacent tentorial leaflet
  • FLAIR signal hyperintensity in a right occipital sulcus and possible adjacent cortical FLAIR signal hyperintensity without definite corresponding restricted diffusion or enhancement (possibly representing leptomeningeal spread)
  • Small focus of restricted diffusion along the falx without definite corresponding enhancement (also possibly a leptomeningeal tumor deposit)
  • Associated mass effect in the posterior fossa resulting in cerebellar tonsillar herniation and crowding of the fourth ventricle with mild obstructive hydrocephalus

Diagnosi

Medulloblastoma - most likely SHH-activated (TP53 wild-type) or Group 4

Diagnosi differenziale

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Perle cliniche

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