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Case #16

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Demographics: 62 years old, Male
Indication: Obtunded, alcoholic cirrhosis

Findings

  • Areas of restricted diffusion and T2/FLAIR hyperintensity in the right greater than left temporal lobes, bilateral hippocampi, bilateral insular cortices, bilateral cingulate gyri, and bilateral orbital frontal lobes
  • Faint T2/FLAIR hyperintensity in the bilateral thalami
  • Background of patchy subcortical and periventricular T2/FLAIR hyperintensity, advanced for age
  • No mass effect, acute hemorrhage, or hydrocephalus

Diagnosis

Hyperammonemic encephalopathy

Sample Report

Multifocal restricted diffusion and T2/FLAIR hyperintensity involving the bilateral temporal lobes, hippocampi, insular cortices, cingulate gyri, orbital frontal lobes, and to a lesser extent the bilateral thalami, which most likely relates to hyperammonemia given clinical history, though encephalitis (including herpes encephalitis) could have a similar appearance. Age-advanced patchy subcortical and periventricular T2/FLAIR hyperintensity, which is nonspecific but commonly attributable to chronic small vessel disease. No mass effect, acute hemorrhage, or hydrocephalus.

Discussion

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